Scroll down to *Research Studies* for Published Research supporting the premise stated by the CDC 

CHRONIC  DISEASES

"Evidence now confirms that noncommunicable chronic diseases can stem from infectious agents. Furthermore, at least 13 of 39 recently described infectious agents induce chronic syndromes. Identifying the relationships can affect health across populations, creating opportunities to reduce the impact of chronic disease by preventing or treating infection. As the concept is progressively accepted, advances in laboratory technology and epidemiology facilitate the detection of noncultivable, novel, and even recognized microbial origins. A spectrum of diverse pathogens and chronic syndromes emerges, with a range of pathways from exposure to chronic illness or disability. Complex systems of changing human behavioral traits superimposed on human, microbial, and environmental factors often determine risk for exposure and chronic outcome. Yet the strength of causal evidence varies widely, and detecting a microbe does not prove causality. Nevertheless, infectious agents likely determine more cancers, immune-mediated syndromes, neurodevelopmental disorders, and other chronic conditions than currently appreciated". Center for Disease Control (CDC)

*RESEARCH  STUDIES  

Research supporting the "Similarities and Paradoxes in Chronic Illnesses" include but are not exclusive to Chronic Fatigue Syndrome, Fibromyalgia , Gulf War Syndrome, Multiple Chemical Illnesses, Lyme Disease and autoimmune diseases. The research supports the premise that we need more research on the infectious connections between all chronic illnesses. The following research studies support the above statement by the CDC. 

BACTERIA OF MEDICAL IMPORTANCE -  Click on following          http://faculty.ksu.edu.sa/5115/Documents/Bacteria.pdf 

------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

Bacterial & Viral Infections - Click on following underlined web addresses for Research studies.                                                                   ( The following reseach information was compiled by Sandi Lanford.)

Evidence for Bacterial ( Mycoplasm , Chlamydia) and Viral ( HHV-6) Co- Infections In Chronic Fatigue Syndrome Patients

http://www.immed.org/illness/fatigue_illness_research.html  

   Chronic Fatigue Syndrome Patients Subsequently Diagnosed with Lyme Disease Borrelia burgdoferi : Evidence for Mycoplasma species Co-Infections                                                                                                                                                                                                                                     www.immed.org

Lyme Disease Presenting as Chronic Fatigue Syndrome                                                                                                                                                      http://www.prohealth.com/library/showarticle.cfm?id=7459&t=CFIDS_FM

Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome

http://www.nih.gov/news/health/oct2009/nci-08.htm

Chronic Lyme Borreliosis at the Root of Multiple Sclerosis - is a Cure with Antibiotics Attainable?

http://www.ncbi.nlm.nih.gov/pubmed/15617845

Cancer

Bacterial Infection as a Cause of Cancer                                                                                             

 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1518971/

How Diarrheal Bacteria Cause Some Colon Cancers Revealed in Mouse Studies

 http://www.sciencedaily.com/releases/2009/08/090823184353.htm

Direct Visualization Propionibacteium Acnes in Prostrate Tissue by Multicolor Fluorescent in Situ Hybridization Assay

 http://www.ncbi.nlm.nih.gov/pubmed/17881550

Alzheimer's 

Alzheimer's Study Leads to Better Drug for Infections                                                                                                                                                                 http://www.medicalnewstoday.com/articles/172132.php

Plaques of Alzheimer's Disease Originate from Cysts of Borrelia burgdorferi the Lyme Disease Spriochete .                                

 http://www.medscape.com/viewarticle/574944_8

Neurologic

Chronic Neurologic Manifestations of Lyme Disease                                                                                                                                                         http://www.ncbi.nlm.nih.gov/pubmed/2172819  

Neurologic Manifestaions of Lyme Disease in the Pediatric Populations

 http://library.lymenet.org/domino/file.nsf/bbf2f15334c1f28585256613000317cc/ c8237a2ae855ba c6852567c700120021 ?OpenDocument

Lyme - Associated Parkinsonism: A Neuroopathologic Case Study & Review of the Literature   -                                                                                 http://arpa.allenpress.com/arpaonline/?request=get-document&doi=10.1043%2F1543- 2165( 2003)127%3C1204:LPANCS%3E2.0.CO%3B2

Researchers Identify Cell Group Key to Lyme Disease Arthritis  -                                                                                                                                          http://www.sciencedaily.com/releases/2008/12/081203184920.htm

 Inflammation

Fibroymalgia , Chronic Fatigue syndrome, and Multiple Chemical Sensitivities                                                                                                          http://www.drmirkin.com/morehealth/g115.htm

Inflammation and Central Nervous System Lyme Disease                                                                                                                                               http://www.ncbi.nlm.nih.gov/pubmed/11558789

New Immune Cell Found to be a Key to Inflammatory Diseases  -                                                                                                                                        http://www.eurekalert.org/pub_releases/2005-10/uotm-nic093005.php

Chronic Inflammation and Amyloidogenesis in Alzheimer's Disease - Role of Spirochetes                                                                                    http://www.ncbi.nlm.nih.gov/pubmed/18487847

J ournal of Alzheimer's Disease                                                                                                                                                                                               http://www.plospathogens.org/article/info:doi%2F10.1371%2Fjournal.ppat.1000659 

High Prevalence of 'Borrelia-like' Organisms in Skin Biopsies of Sarcoidosis                                                                                                              http://www.novoseek.com/DocumentDetailAction.action?docId=19469874&corpus=MEDLINE

Micro-organisms

An Association Between Sciatica and Micro-organisms                                                                                                                                                   http://www.thelancet.com/journals/lancet/article/PIIS0140- 6736( 00)05109-6/abstract

Morgellons disease, illuminating an undefined illness: a case series.  -                                                                                                                                 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737752/

Depression 

Lyme, Depression, and Suicide                                                                                                                                                                                               http://www.mentalhealthandillness.com/Articles/LymeDepressionAndSuicide.htm

Late-Life Depressive Symptoms Are Associated With Both Hyperactivity and Hypoactivity of the Hypothalamo -Pituitary - Adrenal Axis

http://journals.lww.com/ajgponline/Abstract/2007/06000/Late_Life_Depressive_Symptoms_Are_Associated_With.9.aspx

Autoimmune

Infections and Autoimmune Diseases                                                                                                                                                                                                                 

http://www.direct-ms.org/pdf/InfectiousMS/Bach%20Infections%20and%20autoimmunity%20review.pdf

Autoimmune Disease in the era of the Metagenome                                                                                                                                  http://autoimmunityresearch.org/transcripts/AR-Proal-Metagenome.pdf

Bacterial Triggers and Autoimmune Rheumatic Diseases                                                                                                                                                    http://www.ncbi.nlm.nih.gov/pubmed/18570749  

Arthritis 

http://jcm.asm.org/cgi/content/abstract/43/2/850

---------------------------------------------------------------------------------------------------------------------------

RESEARCH LINKS - (Click on Titles for Sites)

Lyme Disease Research Studies

Updated Rates of Common U.S. Neurological Disorders

Cystic Forms of Bb

Borrelia burgdorferi in its various forms

Gestational Lyme borreliosis. Implications for the fetus. MacDonald AB

Transfection "Junk" DNA - a link to the pathogenesis of Alzheimer's disease?

Infection with Multiple Strains of Borrelia

Research done on MS and antibiotic therapy
(Open this page, read the pubmed abstract and look at the right sidebar for more information.)

Studies on Parkinson's

High Blood Pressure Could Be Caused by a Common Virus - CMV

Greater Understanding of Lyme Disease-causing Bacteria

For information on Mycoplasmas go to Professor Garth Nicolson's website:
www.immed.org 

Disclaimer: The mission of LIFELYME is to provide educational information for anyone interested in tick-borne diseases, and related disorders.  Information presented is intended only for educational exchange based on personal medical experience, latest research studies and opinions.  If you are a patient, please ask your own doctor to explain in what manner this information may or may not apply to you.  This information is not offered by LIFELYME as medical advice for anyone.