Scroll down to *Research Studies* for Published Research supporting the premise stated by the CDC .
CHRONIC DISEASES
"Evidence now confirms that noncommunicable chronic diseases can stem from infectious agents. Furthermore, at least 13 of 39 recently described infectious agents induce chronic syndromes. Identifying the relationships can affect health across populations, creating opportunities to reduce the impact of chronic disease by preventing or treating infection. As the concept is progressively accepted, advances in laboratory technology and epidemiology facilitate the detection of noncultivable, novel, and even recognized microbial origins. A spectrum of diverse pathogens and chronic syndromes emerges, with a range of pathways from exposure to chronic illness or disability. Complex systems of changing human behavioral traits superimposed on human, microbial, and environmental factors often determine risk for exposure and chronic outcome. Yet the strength of causal evidence varies widely, and detecting a microbe does not prove causality. Nevertheless, infectious agents likely determine more cancers, immune-mediated syndromes, neurodevelopmental disorders, and other chronic conditions than currently appreciated". Center for Disease Control (CDC)
*RESEARCH STUDIES
Research supporting the "Similarities and Paradoxes in Chronic Illnesses" include but are not exclusive to Chronic Fatigue Syndrome, Fibromyalgia , Gulf War Syndrome, Multiple Chemical Illnesses, Lyme Disease and autoimmune diseases. The research supports the premise that we need more research on the infectious connections between all chronic illnesses. The following research studies support the above statement by the CDC.
BACTERIA OF MEDICAL IMPORTANCE - Click on following http://faculty.ksu.edu.sa/5115/Documents/Bacteria.pdf
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Bacterial & Viral Infections - Click on following underlined web addresses for Research studies. ( The following reseach information was compiled by Sandi Lanford.)
Evidence for Bacterial ( Mycoplasm , Chlamydia) and Viral ( HHV-6) Co- Infections In Chronic Fatigue Syndrome Patients
http://www.immed.org/illness/fatigue_illness_research.html
Examination of Mycoplasmas in Blood of 565 Chronic Illness Patients by Polymerase Chain Reaction
http://www.immed.org/illness/fatigue_illness_research.html
Chronic Fatigue Syndrome Patients Subsequently Diagnosed with Lyme Disease Borrelia burgdoferi : Evidence for Mycoplasma species Co-Infections www.immed.org
Lyme Disease Presenting as Chronic Fatigue Syndrome http://www.prohealth.com/library/showarticle.cfm?id=7459&t=CFIDS_FM
Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome
http://www.nih.gov/news/health/oct2009/nci-08.htm
Chronic Lyme Borreliosis at the Root of Multiple Sclerosis - is a Cure with Antibiotics Attainable?
http://www.ncbi.nlm.nih.gov/pubmed/15617845
Cancer
Bacterial Infection as a Cause of Cancer
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1518971/
How Diarrheal Bacteria Cause Some Colon Cancers Revealed in Mouse Studies
http://www.sciencedaily.com/releases/2009/08/090823184353.htm
Direct Visualization Propionibacteium Acnes in Prostrate Tissue by Multicolor Fluorescent in Situ Hybridization Assay
http://www.ncbi.nlm.nih.gov/pubmed/17881550
Alzheimer's
Alzheimer's Study Leads to Better Drug for Infections http://www.medicalnewstoday.com/articles/172132.php
Plaques of Alzheimer's Disease Originate from Cysts of Borrelia burgdorferi the Lyme Disease Spriochete .
http://www.medscape.com/viewarticle/574944_8
Neurologic
Chronic Neurologic Manifestations of Lyme Disease http://www.ncbi.nlm.nih.gov/pubmed/2172819
Neurologic Manifestaions of Lyme Disease in the Pediatric Populations
http://library.lymenet.org/domino/file.nsf/bbf2f15334c1f28585256613000317cc/ c8237a2ae855ba c6852567c700120021 ?OpenDocument
Lyme - Associated Parkinsonism: A Neuroopathologic Case Study & Review of the Literature - http://arpa.allenpress.com/arpaonline/?request=get-document&doi=10.1043%2F1543- 2165( 2003)127%3C1204:LPANCS%3E2.0.CO%3B2
Researchers Identify Cell Group Key to Lyme Disease Arthritis - http://www.sciencedaily.com/releases/2008/12/081203184920.htm
Inflammation
Fibroymalgia , Chronic Fatigue syndrome, and Multiple Chemical Sensitivities http://www.drmirkin.com/morehealth/g115.htm
Inflammation and Central Nervous System Lyme Disease http://www.ncbi.nlm.nih.gov/pubmed/11558789
New Immune Cell Found to be a Key to Inflammatory Diseases - http://www.eurekalert.org/pub_releases/2005-10/uotm-nic093005.php
Chronic Inflammation and Amyloidogenesis in Alzheimer's Disease - Role of Spirochetes http://www.ncbi.nlm.nih.gov/pubmed/18487847
J ournal of Alzheimer's Disease http://www.plospathogens.org/article/info:doi%2F10.1371%2Fjournal.ppat.1000659
High Prevalence of 'Borrelia-like' Organisms in Skin Biopsies of Sarcoidosis http://www.novoseek.com/DocumentDetailAction.action?docId=19469874&corpus=MEDLINE
Micro-organisms
An Association Between Sciatica and Micro-organisms http://www.thelancet.com/journals/lancet/article/PIIS0140- 6736( 00)05109-6/abstract
Morgellons disease, illuminating an undefined illness: a case series. - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737752/
Depression
Lyme, Depression, and Suicide http://www.mentalhealthandillness.com/Articles/LymeDepressionAndSuicide.htm
Late-Life Depressive Symptoms Are Associated With Both Hyperactivity and Hypoactivity of the Hypothalamo -Pituitary - Adrenal Axis
http://journals.lww.com/ajgponline/Abstract/2007/06000/Late_Life_Depressive_Symptoms_Are_Associated_With.9.aspx
Autoimmune
Infections and Autoimmune Diseases
http://www.direct-ms.org/pdf/InfectiousMS/Bach%20Infections%20and%20autoimmunity%20review.pdf
Autoimmune Disease in the era of the Metagenome http://autoimmunityresearch.org/transcripts/AR-Proal-Metagenome.pdf
Bacterial Triggers and Autoimmune Rheumatic Diseases http://www.ncbi.nlm.nih.gov/pubmed/18570749
Arthritis
http://jcm.asm.org/cgi/content/abstract/43/2/850
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RESEARCH LINKS - (Click on Titles for Sites)
Updated Rates of Common U.S. Neurological Disorders
Borrelia burgdorferi in its various forms
Gestational Lyme borreliosis. Implications for the fetus. MacDonald AB
Transfection "Junk" DNA - a link to the pathogenesis of Alzheimer's disease?
Infection with Multiple Strains of Borrelia
Research done on MS and antibiotic therapy
(Open this page, read the pubmed abstract and look at the right sidebar for more information.)
High Blood Pressure Could Be Caused by a Common Virus - CMV
Greater Understanding of Lyme Disease-causing Bacteria
For information on Mycoplasmas go to Professor Garth Nicolson's website:
www.immed.org
Disclaimer: The mission of LIFELYME is to provide educational information for anyone interested in tick-borne diseases, and related disorders. Information presented is intended only for educational exchange based on personal medical experience, latest research studies and opinions. If you are a patient, please ask your own doctor to explain in what manner this information may or may not apply to you. This information is not offered by LIFELYME as medical advice for anyone.